Description

4-Fluoro-3-Methylbenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a fluorine atom and a nitrile group on a methyl-substituted benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new reactions and creating specialized chemical libraries.
• Dye and Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	4-Fluoro-3-Methylbenzonitrile
CAS No.	185147-08-4
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	3-Methyl-4-fluorobenzonitrile; 4-Fluoro-m-tolunitrile; 4-Fluoro-3-methylbenzenecarbonitrile; 3-Methyl-4-fluorobenzene carbonitrile; 1-Cyano-4-fluoro-3-methylbenzene; 4-Fluoro-3-methylphenyl cyanide; 185147-08-4; 4-Fluoro-3-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	45 - 50 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.