Description

3-Fluoro-2-Methylbenzonitrile is a versatile fluorinated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a fluorine substituent and a nitrile group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis & Chemical Research: Employed in academic and industrial R&D labs for constructing complex fluorinated aromatic compounds and exploring new reaction pathways.
• Functional Material Development: Utilized in the synthesis of specialty polymers, ligands for catalysis, and other advanced materials requiring specific electronic properties.

Basic Information

Product Name	3-Fluoro-2-Methylbenzonitrile
CAS No.	185147-06-2
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	2-Methyl-3-fluorobenzonitrile; 3-Fluoro-o-tolunitrile; 2-Cyano-6-fluorotoluene; 3-Fluoro-2-methylbenzenecarbonitrile; Benzonitrile, 3-fluoro-2-methyl-; (3-Fluoro-2-methylphenyl)cyanide; 185147-06-2 (CAS)
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-2-Methylbenzonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP requirements for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow crystalline solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.