Description

3-Fluoro-4-Piperazinylbenzenecarbonitrile is a high-value pharmaceutical intermediate and fine chemical building block. Its molecular architecture, featuring a piperazine ring and a nitrile group on a fluorinated benzene core, makes it a critical precursor in modern drug discovery and development. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Academic & R&D: Utilized in university and corporate laboratories for methodological development and novel synthetic route exploration.

Basic Information

Product Name	3-Fluoro-4-Piperazinylbenzenecarbonitrile
CAS No.	182181-38-0
Molecular Formula	C11H12FN3
Molecular Weight	205.23 g/mol
Synonyms	4-(3-Fluoro-4-cyanophenyl)piperazine; 3-Fluoro-4-(1-piperazinyl)benzonitrile; 4-Piperazinyl-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-4-(1-piperazinyl)-; 182181-38-0; 3-Fluoro-4-piperazin-1-ylbenzonitrile; 1-(3-Fluoro-4-cyanophenyl)piperazine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Piperazinylbenzenecarbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.