Description

3-Bromo-5-Fluorobenzonitrile is a versatile and high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and brominated components in electronic display and lighting technologies.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of both bromo and cyano functional groups.
• Organic Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorinated and brominated aromatic chemistry.

Basic Information

Product Name	3-Bromo-5-Fluorobenzonitrile
CAS No.	179898-34-1
Molecular Formula	C7H3BrFN
Molecular Weight	200.01 g/mol
Synonyms	5-Bromo-3-Fluorobenzonitrile; 3-Bromo-5-Fluorophenyl Cyanide; Benzonitrile, 3-bromo-5-fluoro-; 1-Bromo-3-cyano-5-fluorobenzene; 3-Fluoro-5-bromobenzonitrile; 179898-34-1; 5-Fluoro-3-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.