Description

5H-Tetrazol-5-One,1-(2-Fluoro-1-Methylcyclopropyl)-1,2-Dihydro-(9Ci) is a specialized heterocyclic organic compound featuring a tetrazole core fused with a fluorinated methylcyclopropyl group. This unique molecular architecture makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the tetrazole ring.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides where the fluorinated cyclopropyl moiety enhances metabolic stability and bioavailability.
• Material Science Precursor: Serves as a precursor for synthesizing specialized ligands, catalysts, or monomers used in advanced polymer and coordination chemistry.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	5H-Tetrazol-5-One,1-(2-Fluoro-1-Methylcyclopropyl)-1,2-Dihydro-(9Ci)
CAS No.	179101-32-7
Molecular Formula	C5H7FN4O
Molecular Weight	158.14 g/mol
Synonyms	1-(2-Fluoro-1-methylcyclopropyl)-1,2-dihydro-5H-tetrazol-5-one; 1-(2-Fluoro-1-methylcyclopropyl)dihydro-5H-tetrazol-5-one; 1-(2-Fluoro-1-methylcyclopropyl)-1,2-dihydro-5H-tetrazol-5-one (9CI); 5H-Tetrazol-5-one, 1-(2-fluoro-1-methylcyclopropyl)-1,2-dihydro-; Tetrazole derivative 179101-32-7; Fluoromethylcyclopropyl tetrazolone
EINECS	Contact for details

Quality Control

Our production of 5H-Tetrazol-5-One,1-(2-Fluoro-1-Methylcyclopropyl)-1,2-Dihydro-(9Ci) adheres to stringent quality protocols suitable for GMP-grade intermediates. Every batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters. Our quality management system is designed to meet the exacting standards of pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.