Description

1-Bromo-2-Fluoro-3-Methyl-5-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in fluorinated and brominated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and bromine atoms enhance biological activity.
• Liquid Crystal Materials: Serves as a crucial building block for synthesizing fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the synthesis of specialized materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Dye and Pigment Industry: Acts as an intermediate for creating complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Bromo-2-Fluoro-3-Methyl-5-Nitrobenzene
CAS No.	175610-68-1
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	2-Bromo-1-Fluoro-6-Methyl-4-Nitrobenzene; 3-Methyl-5-Nitro-1-Bromo-2-Fluorobenzene; 1-Bromo-2-fluoro-3-methyl-5-nitro-benzene; Benzene, 1-bromo-2-fluoro-3-methyl-5-nitro-; 175610-68-1; 2-Fluoro-6-methyl-4-nitro-1-bromobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2-Fluoro-3-Methyl-5-Nitrobenzene is produced and tested under a strict quality management system. We ensure the product meets the high-purity standards required for sensitive synthetic applications. Comprehensive analytical techniques, including HPLC, GC, and NMR, are employed to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.