Description

4-Isopropylamino-3-Nitrobenzotrifluoride is a specialized aromatic trifluoromethyl derivative that serves as a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both a nitro group and an isopropylamino substituent, makes it a critical building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized dyes and pigments, especially those requiring nitro-amino substitution patterns for specific color and fastness properties.
• Liquid Crystal & OLED Material Research: Employed in the research and development of advanced electronic display materials due to its aromatic core and polarizable functional groups.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing specific chemical functionalities into polymer backbones to alter physical properties.
• Chemical Research & Process Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Isopropylamino-3-Nitrobenzotrifluoride
CAS No.	175277-90-4
Molecular Formula	C10H11F3N2O2
Molecular Weight	248.20 g/mol
Synonyms	3-Nitro-4-(isopropylamino)benzotrifluoride; 1-Isopropylamino-2-nitro-4-(trifluoromethyl)benzene; 4-(Isopropylamino)-3-nitro-α,α,α-trifluorotoluene; 2-Nitro-α,α,α-trifluoro-4-(isopropylamino)toluene; N-(2-Nitro-4-(trifluoromethyl)phenyl)propan-2-amine; 4-Isopropylamino-3-nitrobenzotrifluoride; Benzene, 1-(isopropylamino)-2-nitro-4-(trifluoromethyl)-; 175277-90-4
EINECS	Contact for details

Quality Control

Every batch of 4-Isopropylamino-3-Nitrobenzotrifluoride is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure batch-to-batch consistency and high purity. Our standard quality commitment includes providing a detailed Certificate of Analysis (COA) with each shipment, which reports key parameters such as assay, identity, and impurity profiles. For customers with specific regulatory or application requirements, we offer support for customized specifications and can provide samples for qualification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of nitro and amino groups, which may be sensitive, it is recommended to store under an inert atmosphere for long-term stability. Isolate from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.