Description

2-Fluoro-6-(4-Methylphenoxy)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzonitrile core with fluoro and phenoxy substituents. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high selectivity. Pharmaceutical R&D and fine chemical manufacturers need this material for developing new drug candidates, leveraging its molecular scaffold to introduce specific pharmacological properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the synthesis of electron-transport or emissive layers for OLEDs and other organic semiconductor applications.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and exploring new reaction pathways in fluoroorganic chemistry.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services catering to the specific needs of pharmaceutical and agrochemical clients.

Basic Information

Product Name	2-Fluoro-6-(4-Methylphenoxy)Benzonitrile
CAS No.	175204-08-7
Molecular Formula	C14H10FNO
Molecular Weight	227.24 g/mol
Synonyms	2-Fluoro-6-(p-tolyloxy)benzonitrile; 6-Fluoro-2-(4-methylphenoxy)benzonitrile; Benzonitrile, 2-fluoro-6-(4-methylphenoxy)-; 2-Fluoro-6-(4-methylphenoxy)benzonitrile; 175204-08-7; 2-Fluoro-6-(p-methylphenoxy)benzonitrile; 2-Fluoro-6-(4-tolyloxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(4-Methylphenoxy)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.