Description

2-Fluoro-6-(4-Fluorophenoxy)Benzonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a nitrile group and a fluorinated phenoxy linkage, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with enhanced thermal and chemical resistance.
• Organic Electronic Materials: Investigated for use in the development of organic semiconductors and electron-transport materials.
• Chemical Research: A valuable reagent for method development in cross-coupling reactions and nucleophilic aromatic substitution (SNAr) due to its reactive sites.

Basic Information

Product Name	2-Fluoro-6-(4-Fluorophenoxy)Benzonitrile
CAS No.	175204-07-6
Molecular Formula	C13H7F2NO
Molecular Weight	231.20 g/mol
Synonyms	2-Fluoro-6-(4-fluorophenoxy)benzonitrile; 2-Fluoro-6-(p-fluorophenoxy)benzonitrile; Benzonitrile, 2-fluoro-6-(4-fluorophenoxy)-; 1-Fluoro-3-(4-fluorophenoxy)-2-cyanobenzene; 3-Fluoro-2-(4-fluorophenoxy)benzonitrile; 175204-07-6; AKOS005258155
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(4-Fluorophenoxy)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.