Description

2-Fluoro-6-Phenoxybenzonitrile is a high-value fluorinated aromatic nitrile building block used in advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides requiring fluorinated aromatic cores for enhanced activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and the effects of fluorine substitution on aromatic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects.

Basic Information

Product Name	2-Fluoro-6-Phenoxybenzonitrile
CAS No.	175204-06-5
Molecular Formula	C₁₃H₈FNO
Molecular Weight	213.21 g/mol
Synonyms	2-Fluoro-6-phenoxybenzonitrile; Benzonitrile, 2-fluoro-6-phenoxy-; 6-Fluoro-2-phenoxybenzonitrile; 2-Phenoxy-6-fluorobenzonitrile; (2-Fluoro-6-phenoxyphenyl)cyanide; 175204-06-5; 2-Fluoro-6-phenoxy-phenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Phenoxybenzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.