Description

2-Ethoxy-6-(2,2,2-trifluoroethoxy)benzonitrile is a specialized organic compound featuring a benzonitrile core substituted with ethoxy and trifluoroethoxy groups, making it a valuable fluorinated building block. This compound matters for its role in advanced chemical synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoroethoxy moiety enhances efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal, chemical, or surface properties.
• Chemical Research & Development: Employed as a versatile fluorinated aromatic building block in academic and industrial research for exploring new chemical entities.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	2-Ethoxy-6-(2,2,2-trifluoroethoxy)benzonitrile
CAS No.	175204-04-3
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	2-Ethoxy-6-(2,2,2-trifluoroethoxy)benzonitrile; 6-Ethoxy-2-(2,2,2-trifluoroethoxy)benzonitrile; Benzonitrile, 2-ethoxy-6-(2,2,2-trifluoroethoxy)-; 175204-04-3; 2-(2,2,2-Trifluoroethoxy)-6-ethoxybenzonitrile; 6-Ethoxy-2-(trifluoroethoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-6-(2,2,2-trifluoroethoxy)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.