Description

2-Methoxy-6-(2,2,2-trifluoroethoxy)benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its benzonitrile core substituted with methoxy and trifluoroethoxy functional groups. This compound is of significant commercial interest for its role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, pesticides, and fungicides that leverage fluorine chemistry for enhanced efficacy and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for advanced display technologies.
• Organic Synthesis: Employed as a versatile reagent in cross-coupling reactions and other organic transformations to introduce the trifluoroethoxy moiety.
• Material Science: Used in the research and production of specialty polymers and coatings with unique surface properties.

Basic Information

Product Name	2-Methoxy-6-(2,2,2-trifluoroethoxy)benzonitrile
CAS No.	175204-03-2
Molecular Formula	C10H8F3NO2
Molecular Weight	231.17 g/mol
Synonyms	6-Methoxy-2-(2,2,2-trifluoroethoxy)benzonitrile; 2-Methoxy-6-(2,2,2-trifluoroethoxy)phenyl cyanide; 2-Cyano-3-methoxy-1-(2,2,2-trifluoroethoxy)benzene; 175204-03-2; Benzonitrile, 2-methoxy-6-(2,2,2-trifluoroethoxy)-; 2-(Trifluoroethoxy)-6-methoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-(2,2,2-trifluoroethoxy)benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.