Description

2-Fluorobenzene-1,3-Diacetonitrile is a versatile fluorinated aromatic building block characterized by two reactive nitrile groups. This compound is highly valued in advanced organic synthesis for its ability to introduce both fluorine and cyano functionalities into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs), leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine substituent enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to modify electronic properties and stability.
• Chemical Biology Probes: Useful for constructing fluorinated probes and tags for studying biological mechanisms and imaging.

Basic Information

Product Name	2-Fluorobenzene-1,3-Diacetonitrile
CAS No.	175136-84-2
Molecular Formula	C10H7FN2
Molecular Weight	174.18 g/mol
Synonyms	1,3-Bis(cyanomethyl)-2-fluorobenzene; 2-Fluorobenzene-1,3-diacetonitrile; 2-Fluoro-1,3-phenylenediacetonitrile; 2-Fluoro-m-phenylenediacetonitrile; α,α'-(2-Fluoro-1,3-phenylene)diacetonitrile; 2-Fluoro-1,3-di(cyanomethyl)benzene; 2-Fluoroisophthalonitrile (incorrect but common); 2-Fluorobenzene-1,3-dinitrile (common misnomer)
EINECS	Contact for details

Quality Control

Our 2-Fluorobenzene-1,3-Diacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.