Description

1-(4-(Trifluoromethoxy)Phenyl)Cyclopropanecarbonitrile is a high-value, synthetically versatile organic intermediate characterized by its cyclopropane and trifluoromethoxy-substituted aromatic ring system. This compound is prized for its role as a critical building block in modern pharmaceutical and agrochemical research, enabling the introduction of unique steric and electronic properties into target molecules. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a sophisticated scaffold for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its rigid, functionalized structure.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes and tags to study biological processes.

Basic Information

Product Name	1-(4-(Trifluoromethoxy)Phenyl)Cyclopropanecarbonitrile
CAS No.	173859-39-7
Molecular Formula	C11H8F3NO
Molecular Weight	227.18 g/mol
Synonyms	1-[4-(Trifluoromethoxy)phenyl]cyclopropanecarbonitrile; 4-(1-Cyanocyclopropyl)phenyl trifluoromethyl ether; α-(4-Trifluoromethoxyphenyl)cyclopropanenitrile; 1-(4-Trifluoromethoxyphenyl)cyclopropanecarbonitrile; 1-(p-Trifluoromethoxyphenyl)cyclopropanecarbonitrile; 4-(Cyclopropylcarbonitrile)phenyl trifluoromethyl ether; (4-Trifluoromethoxyphenyl)cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(4-(Trifluoromethoxy)Phenyl)Cyclopropanecarbonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We operate under a quality system designed to meet the rigorous standards of our pharmaceutical and advanced R&D customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.