Description

2-Chloro-3,4-difluoronitrobenzene is a versatile halogenated nitrobenzene derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This high-purity intermediate is essential for researchers and manufacturers engaged in creating active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the difluoro and nitro groups impart specific biological activity.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Specialty Dyes and Pigments: Employed in the synthesis of high-performance, light-fast dyes due to its stable aromatic nitro structure.
• Organic Electronic Materials: Used in research and development of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl systems.

Basic Information

Product Name	2-Chloro-3,4-difluoronitrobenzene
CAS No.	169468-83-1
Molecular Formula	C6H2ClF2NO2
Molecular Weight	193.54 g/mol
Synonyms	1-Chloro-2,3-difluoro-4-nitrobenzene; 2,3-Difluoro-1-chloro-4-nitrobenzene; Benzene, 2-chloro-1,3-difluoro-4-nitro-; 2-Chloro-1,3-difluoro-4-nitrobenzene; 3,4-Difluoro-2-chloronitrobenzene; 4-Nitro-2-chloro-1,3-difluorobenzene; 2-Chloro-3,4-difluoro-1-nitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,4-difluoronitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity while monitoring for specified impurities. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.