Description

5-Chloro-1,2-Difluoro-3-Nitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex, high-performance dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct biaryl systems.
• Fluorine Chemistry Studies: A valuable compound for research in fluorination techniques and the study of fluorine's effects on molecular properties.

Basic Information

Product Name	5-Chloro-1,2-Difluoro-3-Nitrobenzene
CAS No.	169468-81-9
Molecular Formula	C6H2ClF2NO2
Molecular Weight	193.54 g/mol
Synonyms	1-Chloro-2,3-difluoro-4-nitrobenzene; 2,3-Difluoro-5-chloronitrobenzene; 3-Nitro-5-chloro-1,2-difluorobenzene; 5-Chloro-2,3-difluoronitrobenzene; Benzene, 5-chloro-1,2-difluoro-3-nitro-; 169468-81-9
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,2-Difluoro-3-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.