Description

Benzeneacetonitrile, .Alpha.-Hydroxy-4-(Trifluoromethyl)- is a high-value, multi-functional chemical intermediate characterized by its trifluoromethyl and hydroxy-substituted benzonitrile structure. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical development. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating specialized fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Advanced Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial R&D for constructing complex molecular architectures and exploring new catalytic transformations.

Basic Information

Product Name	Benzeneacetonitrile, .Alpha.-Hydroxy-4-(Trifluoromethyl)-
CAS No.	168013-75-0
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	2-Hydroxy-2-(4-(trifluoromethyl)phenyl)acetonitrile; α-Hydroxy-4-(trifluoromethyl)benzeneacetonitrile; 4-(Trifluoromethyl)mandelonitrile; (4-Trifluoromethylphenyl)(hydroxy)acetonitrile; 2-(4-Trifluoromethylphenyl)-2-hydroxyacetonitrile; Hydroxy(4-trifluoromethylphenyl)acetonitrile
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetonitrile, .Alpha.-Hydroxy-4-(Trifluoromethyl)- is produced and tested under a strict quality management system. We ensure compliance with rigorous internal specifications, which are designed to meet the high-purity demands of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.