Description

tert-Butyl [2-[(Trifluoroacetyl)Amino]Ethyl]Carbamate is a high-purity, protected amino acid derivative of significant value in advanced organic synthesis. This compound serves as a critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by pharmaceutical companies and contract research organizations (CROs) engaged in peptide mimetics, prodrug development, and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Chemistry: Used for the introduction of protected aminoethyl groups and trifluoroacetyl-protected amines in solid-phase and solution-phase peptide synthesis.
• Prodrug Development: Serves as a precursor for constructing linker systems and cleavable protecting groups in prodrug strategies.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Bioconjugation: Acts as a reagent for modifying biomolecules, enabling the attachment of fluorophores, drugs, or other functional groups.
• Chemical Biology Probes: Utilized in the development of probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	tert-Butyl [2-[(Trifluoroacetyl)Amino]Ethyl]Carbamate
CAS No.	160502-09-0
Molecular Formula	C9H15F3N2O3
Molecular Weight	256.22 g/mol
Synonyms	N-(2-((tert-Butoxycarbonyl)amino)ethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[2-[[(2-methyl-2-propanyl)oxy]carbonyl]amino]ethyl]acetamide; Boc-NH-CH2-CH2-NH-TFA; tert-Butyl N-[2-(2,2,2-trifluoroacetamido)ethyl]carbamate; N-Boc-ethylenediamine trifluoroacetamide; 2-[(tert-Butoxycarbonyl)amino]ethyl trifluoroacetamide; (2-{[(tert-Butoxycarbonyl)amino]}ethyl)amide of trifluoroacetic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl [2-[(Trifluoroacetyl)Amino]Ethyl]Carbamate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.