Description

4-Fluoro-3-Iodobenzonitrile is a versatile and high-purity halogenated benzonitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and cross-coupling reactions, such as Suzuki and Sonogashira couplings.
• Material Science Research: Building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, where halogenated aromatics tune charge transport properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications due to the reactivity of the iodine moiety.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, functionalized aromatic nitriles.

Basic Information

Product Name	4-Fluoro-3-Iodobenzonitrile
CAS No.	159719-57-0
Molecular Formula	C7H3FIN
Molecular Weight	246.01 g/mol
Synonyms	3-Iodo-4-fluorobenzonitrile; 4-Fluoro-3-iodobenzonitrile; Benzonitrile, 4-fluoro-3-iodo-; 4-Fluoro-3-iodo-benzonitrile; 4-Fluoro-3-iodobenzocarbonitrile; 3-Iodo-4-fluorobenzocarbonitrile; 4-Fluoro-3-iodophenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH, FDA guidelines, and other global regulatory frameworks as required for your application.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.