Description

Androsta-1,4-Diene-17-Carboxylic Acid, 9-Fluoro-11,16,17-Trihydroxy-3-Oxo-, (11β,16α,17α)- (9Ci) is a high-purity steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the production of novel glucocorticoid receptor modulators and other potent anti-inflammatory agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing next-generation therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel glucocorticoid and mineralocorticoid receptor agonists/antagonists.
• Research Chemical: Used in biochemical and pharmacological research to study steroid hormone receptor pathways and mechanisms of action.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development of potent topical and systemic anti-inflammatory drugs.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroid-based pharmaceuticals.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Item	Details
Product Name	Androsta-1,4-Diene-17-Carboxylic Acid, 9-Fluoro-11,16,17-Trihydroxy-3-Oxo-, (11β,16α,17α)- (9Ci)
CAS No.	159210-07-8
Molecular Formula	C20H23FO6
Molecular Weight	378.39 g/mol
Synonyms	9-Fluoro-11β,16α,17α-trihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid; 9-Fluoro-11β,16α,17α-trihydroxyprednisolone-17-carboxylic acid; (11β,16α,17α)-9-Fluoro-11,16,17-trihydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid; Fludrocortisone-17-carboxylic acid derivative; 159210-07-8; Prednisolone derivative, 9-fluoro-11,16,17-trihydroxy-3-oxo-17-carboxylic acid
EINECS	Contact for details

Quality Control

Our Androsta-1,4-Diene-17-Carboxylic Acid, 9-Fluoro-11,16,17-Trihydroxy-3-Oxo-, (11β,16α,17α)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.