Description

2,3-Difluoro-6-Nitrobenzonitrile is a high-value, multi-functional aromatic intermediate featuring a strategically substituted benzonitrile core. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. Industries that need it include pharmaceutical R&D for creating novel active ingredients, agrochemical manufacturers developing new crop protection agents, and specialty chemical producers of dyes, pigments, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing difluorinated and nitrile functional groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the nitro and cyano groups contribute to biological activity.
• Material Science Research: Serves as a monomer or building block for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where fluorine and nitro groups modify color properties and lightfastness.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Item	Details
Product Name	2,3-Difluoro-6-Nitrobenzonitrile
CAS No.	157647-01-3
Molecular Formula	C7H2F2N2O2
Molecular Weight	184.10 g/mol
Synonyms	6-Nitro-2,3-difluorobenzonitrile; 2,3-Difluoro-6-nitrobenzenecarbonitrile; Benzonitrile, 2,3-difluoro-6-nitro-; 2,3-Difluoro-6-nitro-benzonitrile; 157647-01-3 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-6-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.