Description

trans-2-Fluoro-4-(4-Vinyl-Cyclohexyl)-Benzonitrile is a specialized fluorinated benzonitrile derivative featuring a vinyl-substituted cyclohexyl group, making it a valuable advanced intermediate for organic synthesis. This compound is engineered to serve as a key building block in the development of high-performance materials and active pharmaceutical ingredients (APIs). It is primarily targeted at research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and liquid crystal display (LCD) industries seeking to incorporate unique fluorinated and rigid structural motifs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, where the fluorine atom and rigid cyclohexyl structure can enhance bioavailability and metabolic stability.
• Liquid Crystal Material Synthesis: Serves as a core component for creating fluorinated mesogens used in high-performance LCDs, improving dielectric anisotropy, viscosity, and overall display performance.
• Agrochemical Active Ingredient Development: Used in research to construct new herbicides or fungicides, leveraging the fluorine atom's ability to modulate lipophilicity and binding affinity to biological targets.
• Advanced Polymer & Material Science: The vinyl group enables polymerization or functionalization, making it suitable for creating specialty polymers, coatings, or functional materials with specific optical or electronic properties.
• Organic Electronic Materials: Investigated as a building block for electron-transport materials or non-linear optical (NLO) chromophores in organic light-emitting diodes (OLEDs) and photonic devices.
• Chemical Research & Process Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new reaction pathways involving fluorinated aromatics.

Basic Information

Product Name	trans-2-Fluoro-4-(4-Vinyl-Cyclohexyl)-Benzonitrile
CAS No.	157453-50-4
Molecular Formula	C15H16FN
Molecular Weight	229.29 g/mol
Synonyms	4-(trans-4-Vinylcyclohexyl)-2-fluorobenzonitrile; 2-Fluoro-4-(4-vinylcyclohexyl)benzonitrile; Benzonitrile, 2-fluoro-4-(4-ethenylcyclohexyl)-, trans-; 4-(4-Vinylcyclohexyl)-2-fluorobenzonitrile; trans-4-(2-Cyano-5-fluorophenyl)vinylcyclohexane; (1r,4r)-4-(2-Cyano-5-fluorophenyl)vinylcyclohexane; 157453-50-4; FC-VCH-BCN (abbreviation)
EINECS	Contact for details

Quality Control

Every batch of trans-2-Fluoro-4-(4-Vinyl-Cyclohexyl)-Benzonitrile is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency, meeting the stringent requirements for advanced intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
trans-Isomer Content (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.