Description

2,6-Dichloro-4-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic intermediate featuring a trifluoromethyl group and two chlorine substituents. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its unique halogenated structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and chloro groups.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of active pharmaceutical ingredients (APIs), particularly in scaffolds requiring halogenated aromatic rings.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands and catalysts used in cross-coupling and other metal-catalyzed reactions.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials where its structural motifs can modify physical properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2,6-Dichloro-4-(trifluoromethyl)benzonitrile
CAS No.	157021-61-9
Molecular Formula	C8H2Cl2F3N
Molecular Weight	240.01 g/mol
Synonyms	4-Cyano-3,5-dichlorobenzotrifluoride; 2,6-Dichloro-α,α,α-trifluoro-p-tolunitrile; 3,5-Dichloro-4-cyanobenzotrifluoride; 2,6-Dichloro-4-(trifluoromethyl)benzenecarbonitrile; Benzonitrile, 2,6-dichloro-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2,6-dichlorobenzonitrile; p-Cyanobenzotrifluoride, 3,5-dichloro-
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-4-(trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.