Description

2-Fluoro-1,3-Dimethoxy-4-Nitrobenzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring fluorine and nitro substituents on a dimethoxybenzene scaffold, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and fluorine atom.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and fluorophores for analytical and imaging applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures common in many functional molecules.

Basic Information

Product Name	2-Fluoro-1,3-Dimethoxy-4-Nitrobenzene
CAS No.	155020-44-3
Molecular Formula	C8H8FNO4
Molecular Weight	201.15 g/mol
Synonyms	1-Fluoro-2,4-Dimethoxy-5-Nitrobenzene; 4-Nitro-2-Fluoro-1,3-Dimethoxybenzene; 5-Nitro-2-Fluoro-1,3-Dimethoxybenzene; Benzene, 2-fluoro-1,3-dimethoxy-4-nitro-; 2-Fluoro-4-nitroresorcinol dimethyl ether
EINECS	Contact for details

Quality Control

Our 2-Fluoro-1,3-Dimethoxy-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.