Description

6,9-Difluoropregn-4-Ene-11,17,21-Triol-3,20-Dione17,21-Diacetate is a high-purity synthetic steroid derivative, specifically a fluorinated pregnane compound. It serves as a critical advanced intermediate in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and anti-inflammatory therapeutics. This compound is essential for pharmaceutical R&D laboratories and fine chemical manufacturers seeking to develop or produce next-generation steroid-based drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated corticosteroid analogs with potential enhanced potency or modified metabolic profiles.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to explore new therapeutic pathways for inflammatory and autoimmune diseases.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating steroid hormone receptor interactions and metabolic pathways due to its specific fluorination pattern.
• Process Chemistry: Utilized as a starting material or intermediate in the scale-up and optimization of synthetic routes for complex steroid molecules.

Basic Information

Item	Detail
Product Name	6,9-Difluoropregn-4-Ene-11,17,21-Triol-3,20-Dione17,21-Diacetate
CAS No.	154802-15-0
Molecular Formula	C₂₅H₃₂F₂O₇
Molecular Weight	482.52 g/mol
Synonyms	6α,9α-Difluoroprednisolone 17,21-Diacetate; 6,9-Difluoroprednisolone 17,21-Diacetate; 6,9-Difluoro-11β,17α,21-trihydroxypregna-4-ene-3,20-dione 17,21-diacetate; 6,9-Difluoro-11β,17,21-trihydroxypregn-4-ene-3,20-dione 17,21-diacetate; 6,9-Difluoropregn-4-ene-3,20-dione-11β,17α,21-triol 17,21-diacetate; 154802-15-0; 6,9-Difluoroprednisolone Diacetate
EINECS	Contact for details

Quality Control

Our 6,9-Difluoropregn-4-Ene-11,17,21-Triol-3,20-Dione17,21-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure compliance with pharmaceutical intermediate standards. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.