Description

1,2-Dihydro Betamethasone 17-Valerate is a key pharmaceutical intermediate and a derivative of the potent corticosteroid betamethasone. This compound is of significant value in the synthesis of advanced topical anti-inflammatory and anti-pruritic medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of dermatological creams, ointments, and other therapeutic formulations targeting skin conditions such as eczema, psoriasis, and dermatitis.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A critical building block in the synthesis of high-potency topical corticosteroids.
• Pharmaceutical Research & Development: Used in preclinical and clinical studies for developing new dermatological drug candidates.
• Dermatological Formulations: Incorporated into the manufacture of creams, ointments, lotions, and gels for treating inflammatory skin disorders.
• Veterinary Medicine: Applied in the formulation of topical treatments for skin conditions in animals.
• Reference Standard: Serves as a chromatographic reference standard for quality control and analytical testing in pharmaceutical labs.

Basic Information

Product Name	1,2-Dihydro Betamethasone 17-Valerate
CAS No.	154713-07-2
Molecular Formula	C₂₇H₃₇FO₆
Molecular Weight	476.58 g/mol
Synonyms	Betamethasone 17-Valerate Dihydro Derivative; 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-valerate; 1,2-Dihydrobetamethasone 17-valerate; 1,2-Dihydrobetamethasone valerate; Betamethasone 17-valerate impurity; Betamethasone valerate related compound
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro Betamethasone 17-Valerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.