Description

Alinastine is a potent and selective histamine H1-receptor antagonist with significant anti-inflammatory properties. This compound is of critical importance in pharmaceutical research and development for its targeted mechanism of action. It is primarily needed by pharmaceutical companies and research institutions engaged in developing novel therapeutics for allergic and inflammatory conditions, such as allergic rhinitis, asthma, and atopic dermatitis.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) in the synthesis of anti-allergy medications.
• Biochemical Research: Used as a reference standard and tool compound in pharmacological studies of histamine receptor pathways.
• Drug Discovery: A vital candidate for preclinical development of new anti-inflammatory and anti-allergic drugs.
• Ophthalmic Solutions: Investigated for use in formulations targeting allergic conjunctivitis.
• Topical Formulations: Potential application in creams or ointments for treating skin allergies and inflammation.
• Veterinary Medicine: Exploration of use in treating allergic conditions in animals.

Basic Information

Product Name	Alinastine
CAS No.	154541-72-7
Molecular Formula	C22H24N4O3
Molecular Weight	392.45 g/mol
Synonyms	Alinastine; 2-[2-[4-(Diphenylmethoxy)-1-piperidinyl]ethyl]-4(3H)-quinazolinone; KW-4679; 4(3H)-Quinazolinone, 2-[2-[4-(diphenylmethoxy)-1-piperidinyl]ethyl]-; UNII-8Z4C66Y3QN; Alinastinum; Alinastina
EINECS	Contact for details

Quality Control

Our Alinastine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and provided upon request, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.