Description

Abiraterone Acetate CAS NO 154229-18-2 is a high-purity, steroidal active pharmaceutical ingredient (API) that functions as a potent and selective inhibitor of CYP17A1. This compound is critical for the targeted treatment of metastatic castration-resistant prostate cancer (mCRPC) by blocking androgen biosynthesis. It is an essential raw material for pharmaceutical manufacturers developing and producing advanced oncology therapeutics.

Application

• Primary active pharmaceutical ingredient (API) in the formulation of oral anti-cancer medications.
• Key intermediate in the synthesis of finished dosage forms, such as tablets and capsules, for prostate cancer therapy.
• Critical component in research and development of novel hormonal therapies for oncology.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Used in clinical trial material manufacturing for investigational new drug (IND) applications.
• Essential for the production of generic versions of approved abiraterone acetate drugs.

Basic Information

Item	Details
Product Name	Abiraterone Acetate
CAS No.	154229-18-2
Molecular Formula	C26H33NO2
Molecular Weight	391.55 g/mol
Synonyms	Abiraterone 3β-Acetate; 17-(3-Pyridyl)androsta-5,16-dien-3β-yl acetate; CB-7630; Zytiga (Brand Name API); (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-yl acetate
EINECS	Contact for details

Quality Control

Our Abiraterone Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical standards, including specifications for identity, assay, and impurity profiles. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial monographs (e.g., USP, EP) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.