Description

4-Methyl-2-Nitro-1-(Trifluoromethyl)Benzene is a specialized aromatic compound featuring a nitro group and a trifluoromethyl substituent, making it a valuable fluorinated building block for advanced chemical synthesis. Its unique structure is critical for introducing both electron-withdrawing and lipophilic properties into target molecules, which is essential for modulating the physical and biological activity of final products. This high-purity intermediate is primarily sought by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for introducing the trifluoromethyl group to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups contribute to efficacy and environmental profile.
• Material Science Research: Acts as a precursor for synthesizing advanced organic materials, including liquid crystals, polymers, and electronic chemicals that require specific fluorinated aromatic units.
• Chemical Research & Development: Employed as a standard or building block in organic synthesis for method development and creating complex molecular architectures in academic and industrial R&D settings.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where the nitro group is integral to color formation and the CF3 group alters solubility and fastness properties.

Basic Information

Product Name	4-Methyl-2-Nitro-1-(Trifluoromethyl)Benzene
CAS No.	154057-13-3
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-Nitro-α,α,α-trifluoro-p-xylene; 1-Methyl-4-(trifluoromethyl)-2-nitrobenzene; 4-Methyl-2-nitrobenzotrifluoride; 2-Nitro-4-methylbenzotrifluoride; α,α,α-Trifluoro-2-nitro-p-xylene; 4-(Trifluoromethyl)-2-nitrotoluene; 2-Nitro-α,α,α-trifluoro-4-methyltoluene; Benzene, 1-methyl-4-(trifluoromethyl)-2-nitro-
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-2-Nitro-1-(Trifluoromethyl)Benzene adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.