Description

D-Gluconic Acid, 3,6-Anhydro-2-Deoxy-2-Fluoro-, γ-Lactone (9Ci) is a specialized fluorinated sugar derivative, a key building block in synthetic carbohydrate chemistry. Its value lies in the strategic introduction of a fluorine atom and an anhydro bridge, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel nucleoside analogs, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and antiviral/anticancer prodrugs.
• Biochemical Research: Used as a probe or substrate in enzymatic studies to investigate glycosidase and glycosyltransferase mechanisms.
• Medicinal Chemistry: Serves as a scaffold for developing new chemical entities (NCEs) targeting carbohydrate-processing enzymes.
• Agrochemical Synthesis: Potential intermediate for creating novel fluorinated pesticides or herbicides with enhanced properties.
• Glycobiology Tool: Employed in the study of cell-surface interactions and the development of carbohydrate-based diagnostics.

Basic Information

Item	Details
Product Name	D-Gluconic Acid, 3,6-Anhydro-2-Deoxy-2-Fluoro-, γ-Lactone (9Ci)
CAS No.	152714-94-8
Molecular Formula	C6H7FO5
Molecular Weight	178.12 g/mol
Synonyms	2-Deoxy-2-fluoro-3,6-anhydro-D-glucono-1,5-lactone; 3,6-Anhydro-2-deoxy-2-fluoro-D-glucono-1,5-lactone; 2-Fluoro-2-deoxy-3,6-anhydro-D-gluconolactone; Fluorinated anhydro gluconolactone; (3aR,5R,6S,6aR)-5-(Fluoromethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol (related structure); 9CI compound 152714-94-8
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development use. Our standard quality control includes identity confirmation by spectroscopic methods (NMR, IR) and purity assessment by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment. Specifications can be developed in alignment with cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.