Description

Bevantolol Hydrochloride CAS NO 152510-36-6 is a selective β-1 adrenergic receptor antagonist (β-blocker) in its hydrochloride salt form, offering enhanced stability and solubility for pharmaceutical development. This compound is critical for research and development in cardiovascular pharmacology, serving as a key intermediate or active pharmaceutical ingredient (API). It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing treatments for hypertension, angina, and other cardiac conditions.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of β-blocker medications.
• Cardiovascular Research: Used in preclinical and clinical studies to investigate mechanisms of β-1 adrenergic blockade.
• Reference Standard: Serves as a high-purity standard for analytical testing, quality control, and method validation in laboratories.
• Intermediate Synthesis: Key building block in the multi-step synthesis of more complex pharmaceutical compounds.
• Dosage Form Development: Utilized in the development of various drug delivery systems such as tablets and capsules.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research.

Basic Information

Product Name	Bevantolol Hydrochloride
CAS No.	152510-36-6
Molecular Formula	C20H27NO4 • HCl
Molecular Weight	381.89 g/mol
Synonyms	Bevantolol HCl; 1-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-methylphenoxy)-2-propanol Hydrochloride; (±)-Bevantolol Hydrochloride; DL-Bevantolol Hydrochloride; Sentiloc Hydrochloride; NC-1400; Vantol
EINECS	Contact for details

Quality Control

Our Bevantolol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and related substances, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets stringent specifications. Certificates of Analysis (COA) documenting compliance with in-house pharmacopeial standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.