Description

Proxodolol CAS NO 152289-58-2 is a specialized organic compound belonging to the class of β-adrenergic receptor ligands. This high-purity intermediate is of significant value in pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents targeting cardiovascular and neurological pathways. It is primarily sought after by R&D laboratories, contract manufacturing organizations (CMOs), and pharmaceutical companies engaged in the development of advanced drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary β-blocker or related active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Biochemical Research: Serves as a reference standard or a ligand in pharmacological assays to study adrenergic receptor interactions.
• Contract Synthesis: Supplied to CMOs for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	Proxodolol
CAS No.	152289-58-2
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	1-(1,1-Dimethylethylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]-2-propanol; 4-[2-[(tert-Butylamino)-1-hydroxyethyl]oxy]-2-methyl-1H-indole; Proxodolol [USAN]; Proxodololum; UNII-6E6K5L671U
EINECS	Contact for details

Quality Control

Our Proxodolol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent research and development standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.