Description

o-Flutamide is a non-steroidal antiandrogen compound of significant interest in pharmaceutical research and development. Its primary value lies in its role as a key intermediate or reference standard for the synthesis and study of more complex therapeutic agents targeting androgen receptors. This compound is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in developing treatments for conditions like prostate cancer and androgen-dependent disorders. The consistent high purity of our o-Flutamide ensures reliable and reproducible results in critical research and production processes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced antiandrogen drugs and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in studies investigating androgen receptor binding, function, and signaling pathways.
• Preclinical Development: Employed in the development and validation of new therapeutic candidates for hormone-related cancers and conditions.
• Analytical Standard: Provides a high-purity benchmark for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical laboratories.
• Fine Chemical Synthesis: Utilized in custom synthesis and process chemistry for creating specialized fluorinated organic molecules.

Basic Information

Product Name	o-Flutamide
CAS No.	151262-93-0
Molecular Formula	C11H11F3N2O3
Molecular Weight	276.21 g/mol
Synonyms	2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide; 2-Methyl-4'-nitro-3'-(trifluoromethyl)propionanilide; ortho-Flutamide; Flutamide Impurity; Flutamide Related Compound A; α,α,α-Trifluoro-2-methyl-4'-nitro-m-propionotoluidide; NSC 147834
EINECS	Contact for details

Quality Control

Our o-Flutamide is manufactured under strict quality management systems to ensure it meets the high standards required for research and pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters. We support cGMP-compliant production for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.