Description

Efletirizine is a high-purity pharmaceutical intermediate and active ingredient, identified by CAS No. 150756-35-7. It is a critical compound valued for its role in the synthesis of advanced antihistamine medications. This product is essential for pharmaceutical manufacturers and research institutions focused on developing and producing new therapeutic agents for allergic conditions.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of novel, non-sedating antihistamine drugs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key building block in R&D for new allergy and inflammation treatments.
• Clinical Research: Utilized in preclinical and clinical studies to investigate pharmacokinetics and efficacy.
• Reference Standard: Acts as a high-purity standard for analytical method development and quality control in pharmaceutical labs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production.

Basic Information

Item	Detail
Product Name	Efletirizine
CAS No.	150756-35-7
Molecular Formula	C21H25ClN2O3
Molecular Weight	388.89 g/mol
Synonyms	Efletirizine; 2-[2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid; Levocetirizine Impurity; (R)-Cetirizine; (R)-2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid; UCB 28556; Cetirizine Related Compound R
EINECS	Contact for details

Quality Control

Our Efletirizine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We adhere to ICH guidelines and relevant pharmacopeial standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA), detailing identity, purity, and impurity profiles, is provided with each shipment to support your regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.