Description

Dexamethasone Beloxil is a high-purity synthetic glucocorticoid derivative, specifically the 21-acetate ester of dexamethasone. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, offering enhanced stability and bioavailability for advanced pharmaceutical formulations. It is a critical intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing targeted corticosteroid therapies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of advanced dexamethasone prodrugs and ester derivatives.
• Anti-inflammatory Drug Development: Used in R&D for formulating potent topical, oral, and injectable anti-inflammatory medications.
• Immunosuppressive Therapy: A component in research for drugs targeting autoimmune disorders, organ transplantation, and certain cancers.
• Reference Standard: Used as an analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.
• Biochemical Research: A tool compound for studying glucocorticoid receptor (GR) signaling pathways and gene expression regulation.

Basic Information

Product Name	Dexamethasone Beloxil
CAS No.	150587-07-8
Molecular Formula	C24H31FO6
Molecular Weight	434.50 g/mol
Synonyms	Dexamethasone 21-Acetate; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate; Dexamethasone Acetate; Dexamethasone 21-O-acetate; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-acetate; 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione 21-acetate
EINECS	Contact for details

Quality Control

Our Dexamethasone Beloxil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), assay (HPLC), and impurity profiling to ensure it meets high-purity standards suitable for pharmaceutical R&D and GMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.