Description

Celiprolol Fd is a high-purity active pharmaceutical ingredient (API) belonging to the class of cardioselective β-1 adrenergic receptor blockers. This compound is critical for the formulation of cardiovascular medications, offering precise therapeutic action. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for hypertension and angina pectoris. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final drug product.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for cardiovascular diseases.
• Hypertension Treatment: Formulation into tablets or capsules for managing high blood pressure.
• Angina Pectoris Therapy: Used in medications to prevent chest pain caused by reduced blood flow to the heart.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in laboratories.
• Clinical Research: Utilized in preclinical and clinical studies for developing new cardiovascular drug formulations.
• Generic Drug Manufacturing: A key component in the production of generic versions of β-blocker medications.

Basic Information

Product Name	Celiprolol Fd
CAS No.	149825-34-3
Molecular Formula	C20H33N3O4
Molecular Weight	379.50 g/mol
Synonyms	Celiprolol; Celiprolol Hydrochloride; (±)-Celiprolol; DL-Celiprolol; 3-[3-Acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea; Selectol; Cardem; Celectol; Corrector
EINECS	Contact for details

Quality Control

Our Celiprolol Fd is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, aligning with major pharmacopoeial standards such as USP and EP. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single unknown impurity ≤ 0.2%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.