Description

2-Fluoro-6-[4-(Methylthio)Phenoxy]Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzonitrile core substituted with fluoro and methylthiophenoxy groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling precise molecular modifications essential for modern drug discovery. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated fluorinated aromatic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Serves as a structural motif in the development of new-generation herbicides and pesticides, leveraging its fluorinated aromatic system.
• Material Science: Used in the research and development of specialty polymers and liquid crystals, where its molecular structure can influence material properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules via cross-coupling and nucleophilic substitution reactions.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2-Fluoro-6-[4-(Methylthio)Phenoxy]Benzonitrile
CAS No.	148901-52-4
Molecular Formula	C14H10FNOS
Molecular Weight	259.30 g/mol
Synonyms	2-Fluoro-6-(4-methylsulfanylphenoxy)benzonitrile; 2-Fluoro-6-(p-methylthiophenoxy)benzonitrile; Benzonitrile, 2-fluoro-6-[4-(methylthio)phenoxy]-; 148901-52-4; 2-Fluoro-6-(4-(methylthio)phenoxy)benzonitrile; 2-Fluoro-6-(4-methylmercaptophenoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-[4-(Methylthio)Phenoxy]Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.