Description

2-Propanol, 1-[4-(2-Methoxyethyl)Phenoxy]-3-[(1-Methylethyl)Amino]-, (S)-, [R-(R*,R*)]-2,3-Dihydroxybutanedioate (2:1) (Salt) is a high-purity, non-racemic salt form of a complex amino alcohol derivative, designed for advanced pharmaceutical synthesis and research. This compound is valued for its role as a key chiral intermediate or active pharmaceutical ingredient (API) in the development of targeted therapeutics. It is primarily required by pharmaceutical R&D laboratories, process chemists, and manufacturers engaged in the production of sophisticated small-molecule drugs, particularly those targeting cardiovascular or neurological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• β-Blocker Research: Used in the research and development of next-generation β-adrenergic blocking agents (β-blockers) due to its structural motif.
• Process Chemistry: Employed in route scouting, optimization, and scale-up activities for new chemical entities (NCEs).
• Chiral Catalyst or Ligand Precursor: May be utilized to develop or synthesize chiral catalysts or ligands for asymmetric synthesis.
• Reference Standard: Functions as a high-purity chemical reference standard for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Biochemical Research: Applied in studies investigating adrenergic receptor interactions and signal transduction mechanisms.

Basic Information

Product Name	2-Propanol, 1-[4-(2-Methoxyethyl)Phenoxy]-3-[(1-Methylethyl)Amino]-, (S)-, [R-(R*,R*)]-2,3-Dihydroxybutanedioate (2:1) (Salt)
CAS No.	148507-73-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol (2R,3R)-2,3-dihydroxybutanedioate (2:1); (S)-Esmolol Tartrate; Esmolol (S)-enantiomer Tartrate Salt; 1-[4-(2-Methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol (2S)-2,3-dihydroxybutanedioate; ASL-8052 (related to tartrate salt); Methyl 3-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]propanoate Tartrate Derivative
EINECS	Contact for details

Quality Control

Our 2-Propanol, 1-[4-(2-Methoxyethyl)Phenoxy]-3-[(1-Methylethyl)Amino]-, (S)-, [R-(R*,R*)]-2,3-Dihydroxybutanedioate (2:1) (Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assay and impurity profiling, to ensure it meets exacting pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and related substances are provided to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (anhydrous basis)
Chiral Purity (Chiral HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.