Description

2-Propanol, 1-[4-(2-Methoxyethyl)Phenoxy]-3-[(1-Methylethyl)Amino]-, (R)-, [R-(R*,R*)]-2,3-Dihydroxybutanedioate (2:1) (Salt) is a high-purity, single-enantiomer chemical intermediate of significant importance in advanced pharmaceutical synthesis. This compound, identified by CAS number 148507-72-6, is valued for its defined stereochemistry and role as a key building block in the development of active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the production of specialized therapeutics.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of complex, stereospecific Active Pharmaceutical Ingredients (APIs).
• β-Blocker Research & Development: Serves as a key precursor in the development and production of certain classes of cardiovascular drugs.
• Asymmetric Synthesis: Utilized in advanced organic synthesis where control of stereochemistry is paramount for biological activity.
• Process Chemistry & Scale-Up: Employed in process development and optimization for the commercial manufacturing of target molecules.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Fine Chemical Synthesis: Applied in the production of other specialized, high-value chemical entities beyond pharmaceuticals.

Basic Information

Item	Details
Product Name	2-Propanol, 1-[4-(2-Methoxyethyl)Phenoxy]-3-[(1-Methylethyl)Amino]-, (R)-, [R-(R*,R*)]-2,3-Dihydroxybutanedioate (2:1) (Salt)
CAS No.	148507-72-6
Molecular Formula	C17H27NO5 • 0.5C4H6O6
Molecular Weight	Contact for details
Synonyms	(R)-1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol (2:1) tartrate salt; (R)-1-[4-(2-Methoxyethyl)phenoxy]-3-(isopropylamino)-2-propanol tartrate; (R)-1-[4-(2-Methoxyethyl)phenoxy]-3-(isopropylamino)propan-2-ol tartrate; (R)-Mepindolol Tartrate; Mepindolol (R)-enantiomer tartrate; (R)-Mepindolol Hydrogen Tartrate; (2R)-1-[4-(2-Methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol tartrate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis and impurity profiling by HPLC, to ensure identity, strength, and quality. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We operate under a GMP-compliant quality management system to guarantee traceability and consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (R-enantiomer)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.