Description

n-Fluoro-5-(Trifluoromethyl)Pyridinium-2-Sulfonate is a high-value, fluorinated pyridinium salt derivative, serving as a critical building block and reagent in advanced synthetic chemistry. Its unique structure, featuring both a reactive sulfonate group and a stable fluorinated pyridinium core, makes it an essential precursor for introducing fluorinated motifs into complex molecules. This compound is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty materials sectors for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorine atoms to improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorinated compounds offer superior activity and environmental profile.
• Fluorination Reagent: Acts as a source of fluorine or a fluorinated pyridine moiety in nucleophilic or electrophilic fluorination reactions under controlled conditions.
• Ligand & Catalyst Precursor: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Material Science Research: Investigated for incorporation into polymers, liquid crystals, and electronic materials to impart specific dielectric or surface properties.
• Chemical Biology Probes: Serves as a building block for creating fluorinated probes and tags used in bioimaging and mechanistic studies.

Basic Information

Product Name	n-Fluoro-5-(Trifluoromethyl)Pyridinium-2-Sulfonate
CAS No.	147541-08-0
Molecular Formula	C7H4F4NO3S
Molecular Weight	258.17 g/mol
Synonyms	5-(Trifluoromethyl)-2-fluoropyridinium-1-sulfonate; 2-Fluoro-5-(trifluoromethyl)pyridinium sulfonate; 1-(2-Fluoro-5-(trifluoromethyl)pyridin-1-ium-1-yl)methanesulfonate; N-Fluoro-5-trifluoromethylpyridinium-2-sulfonate; FTFP-Sulfonate; 2-Fluoro-5-(trifluoromethyl)pyridine methanesulfonate
EINECS	Contact for details

Quality Control

Our n-Fluoro-5-(Trifluoromethyl)Pyridinium-2-Sulfonate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements of research and process development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.