Description

n-(3-Pyridylmethyl)Dihydroepidoxorubicin is a structurally modified derivative of the potent anthracycline antibiotic, doxorubicin. This compound is of significant interest in pharmaceutical research and development due to its potential for altered pharmacokinetics, reduced cardiotoxicity, and targeted therapeutic efficacy. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel oncology treatments and advanced drug delivery systems.

Application

• Oncology Research: Serves as a key intermediate or active pharmaceutical ingredient (API) in preclinical studies for novel anti-cancer therapies.
• Drug Discovery: Used in structure-activity relationship (SAR) studies to develop anthracycline analogs with improved safety and efficacy profiles.
• Biochemical Research: Employed as a tool compound to study mechanisms of action involving topoisomerase II inhibition and DNA intercalation.
• Pharmaceutical Development: Investigated for use in targeted drug delivery systems, such as antibody-drug conjugates (ADCs) or nanoparticle formulations.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and pharmacology.

Basic Information

Product Name	n-(3-Pyridylmethyl)Dihydroepidoxorubicin
CAS No.	145785-63-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3'-Pyridylmethyl Dihydroepidoxorubicin; 3'-Pyridylmethyl Epidoxorubicin Derivative; N-(Pyridin-3-ylmethyl)dihydroepidoxorubicin; Doxorubicin, N-[(3-pyridinyl)methyl]dihydro-; Epidoxorubicin Pyridylmethyl Derivative
EINECS	Contact for details

Quality Control

Our n-(3-Pyridylmethyl)Dihydroepidoxorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, keep desiccated under an inert atmosphere. The product is hygroscopic and may degrade if exposed to moisture or elevated temperatures.

Specification

Item	Specification
Appearance	Red to orange solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.