Description

3(2H)-Isoxazolone,4-Methyl-5-(Trifluoromethyl)-(9Ci) is a specialized heterocyclic building block containing a trifluoromethyl group, a key structural motif prized for its ability to modulate the physicochemical properties of target molecules. This compound is valued for its role as a versatile intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where the introduction of fluorine atoms can enhance metabolic stability, bioavailability, and binding affinity. It is primarily sought by research and development chemists and process engineers in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzymes and receptors where the trifluoromethyl group is beneficial.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the isoxazolone core and fluorine atoms contribute to efficacy and environmental profile.
• Fine Chemical Building Block: Serves as a versatile precursor in custom synthesis and the manufacture of complex organic molecules for various high-value industrial applications.
• Material Science Research: Investigated for the development of specialty polymers, liquid crystals, or organic electronic materials due to its unique heterocyclic and fluorinated structure.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe in life science research to study biological pathways and interactions.

Basic Information

Product Name	3(2H)-Isoxazolone,4-Methyl-5-(Trifluoromethyl)-(9Ci)
CAS No.	145433-09-6
Molecular Formula	C5H4F3NO2
Molecular Weight	167.09 g/mol
Synonyms	4-Methyl-5-(trifluoromethyl)-3(2H)-isoxazolone; 5-(Trifluoromethyl)-4-methyl-3(2H)-isoxazolone; 4-Methyl-5-trifluoromethyl-2H-isoxazol-3-one; 3-Hydroxy-4-methyl-5-(trifluoromethyl)isoxazole; 4-Methyl-5-(trifluoromethyl)isoxazol-3(2H)-one; 145433-09-6; 4-Methyl-5-trifluoromethyl-3-isoxazolone
EINECS	Contact for details

Quality Control

Our 3(2H)-Isoxazolone,4-Methyl-5-(Trifluoromethyl)-(9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical specifications such as assay and impurity profiles. We are committed to meeting the stringent requirements of research and cGMP-guided production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.