Description

Antazoline Nitrate is a high-purity pharmaceutical-grade compound, primarily recognized for its potent antihistaminic and anticholinergic properties. This makes it a critical active pharmaceutical ingredient (API) for the formulation of ophthalmic solutions and nasal sprays designed to relieve allergic conjunctivitis and rhinitis. It is essential for manufacturers in the pharmaceutical and ophthalmic industries seeking reliable, high-quality raw materials for sensitive therapeutic applications. Our supply ensures consistent purity and stability, meeting the stringent demands of global regulatory standards.

Application

• Primary Active Pharmaceutical Ingredient (API) in ophthalmic solutions for treating allergic conjunctivitis.
• Key component in nasal decongestant sprays for allergic rhinitis relief.
• Used in veterinary pharmaceutical formulations for allergic conditions in animals.
• Intermediate in the research and synthesis of novel antihistamine derivatives.
• Reference standard in analytical laboratories for quality control and method development.
• Ingredient in certain topical anti-itch creams and dermatological preparations.

Basic Information

Product Name	Antazoline Nitrate
CAS No.	145178-44-5
Molecular Formula	C17H19N3·HNO3
Molecular Weight	329.36 g/mol
Synonyms	Antazoline Mononitrate; 2-[(4-Methylphenyl)phenylmethoxy]-N,N-dimethylethanamine Nitrate; N,N-Dimethyl-2-[(phenyl-p-tolyl-methoxy)ethyl]amine Nitrate; Antasten; Phenazoline; Antistin; Imidamin; Antazoline (as nitrate); Antazoline Nitrate Salt
EINECS	Contact for details

Quality Control

Our Antazoline Nitrate is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Each batch undergoes rigorous analytical testing including identity confirmation, purity assay, and impurity profiling to ensure it meets precise specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.