Description

2-[N,n-Bis(Trifluoromethylsulfonyl)Amino]Pyridine is a specialized organofluorine compound featuring a highly electron-withdrawing bis(triflyl)amide (NTf2) group attached to a pyridine nitrogen. This structure makes it a valuable reagent and intermediate in advanced organic synthesis, particularly for introducing the robust NTf2 moiety or as a precursor to novel ionic liquids and catalysts. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for developing new chemical entities and high-performance materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where the introduction of a sulfonamide or trifluoromethylsulfonyl group is required for bioactivity or metabolic stability.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Precursor: Employed in the development of specialized ligands for transition metal catalysis and as a precursor for generating novel ionic liquid catalysts.
• Electrolyte Additive Research: Investigated for use in lithium-ion battery electrolytes to improve stability and performance at high voltages.
• Polymer Modification: Used to functionalize polymers, imparting specific properties such as increased thermal stability or altered solubility.
• Organic Electronics: Acts as a dopant or charge-transport material component in the research and development of organic light-emitting diodes (OLEDs) and other electronic devices.

Basic Information

Product Name	2-[N,n-Bis(Trifluoromethylsulfonyl)Amino]Pyridine
CAS No.	145100-50-1
Molecular Formula	C8H4F6N2O4S2
Molecular Weight	370.25 g/mol
Synonyms	2-(Bis(trifluoromethylsulfonyl)amino)pyridine; 2-Pyridylbis(trifluoromethanesulfonyl)imide; 2-(N,N-Bis(trifluoromethanesulfonyl)amino)pyridine; Pyridine, 2-[bis[(trifluoromethyl)sulfonyl]amino]-; 2-(TFSI)aminopyridine; 2-NTf2-Pyridine; N-(Pyridin-2-yl)-1,1,1-trifluoro-N-((trifluoromethyl)sulfonyl)methanesulfonamide
EINECS	Contact for details

Quality Control

Our 2-[N,n-Bis(Trifluoromethylsulfonyl)Amino]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.