Description

2,3,4-Trifluorobenzonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique trifluorinated pattern on the benzonitrile core makes it a critical intermediate for introducing fluorine atoms into complex molecules, enhancing their metabolic stability, lipophilicity, and binding affinity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine substitution improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Electronics: Employed in the synthesis of electron-deficient units for organic semiconductors and OLED materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating specialized chemical libraries.
• Advanced Polymer Chemistry: Acts as a monomer or modifier to introduce fluorine functionality into polymers, enhancing chemical and thermal resistance.

Basic Information

Product Name	2,3,4-Trifluorobenzonitrile
CAS No.	143879-80-5
Molecular Formula	C7H2F3N
Molecular Weight	157.09 g/mol
Synonyms	2,3,4-Trifluorobenzonitrile; 2,3,4-Trifluorobenzene carbonitrile; Benzonitrile, 2,3,4-trifluoro-; 2,3,4-Trifluorophenyl cyanide; 2,3,4-Trifluorobenzonitrile (CAS 143879-80-5); 2,3,4-Trifluoro cyanobenzene; 3,4,5-Trifluorobenzonitrile (isomer); α,2,3,4-Tetrafluorotoluene nitrile analog
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.