Description

2,6-Difluoro-3-Nitrobenzonitrile is a high-purity fluorinated aromatic nitrile building block, identified by CAS NO 143879-77-0. This compound is valued for its unique substitution pattern, which makes it a critical intermediate in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs). It is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical manufacturing sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its electron-withdrawing nitro and nitrile groups.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and nucleophilic aromatic substitution to introduce functionalized aromatic rings into target molecules.

Basic Information

Product Name	2,6-Difluoro-3-Nitrobenzonitrile
CAS No.	143879-77-0
Molecular Formula	C7H2F2N2O2
Molecular Weight	184.10 g/mol
Synonyms	3-Nitro-2,6-difluorobenzonitrile; 2,6-Difluoro-3-nitrobenzenecarbonitrile; Benzonitrile, 2,6-difluoro-3-nitro-; 143879-77-0; 2,6-Difluoro-3-nitro-benzonitrile
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.