Description

Benzonitrile, 4-Isocyanato-2-(Trifluoromethyl)- is a specialized aromatic isocyanate derivative, distinguished by the presence of a reactive isocyanate group and a trifluoromethyl substituent. This molecular architecture makes it a high-value building block for synthesizing advanced materials with tailored properties. It is primarily sought after by R&D and production chemists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with enhanced bioactivity or specific physical characteristics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for improved metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the trifluoromethyl group can enhance efficacy and environmental profile.
• Specialty Polymer & Resin Production: Serves as a monomer or cross-linking agent for producing polyurethanes, polyureas, and other high-performance polymers with specific chemical resistance or surface properties.
• Liquid Crystal & OLED Material Development: Incorporated into the molecular design of advanced electronic display materials to modify dielectric constants and alignment properties.
• Organic Synthesis & Chemical Research: A versatile reagent for introducing the isocyanato and trifluoromethylphenyl groups into complex molecules in academic and industrial R&D settings.
• Surface Modification & Coating Additive: Can be used to functionalize surfaces or act as an adhesion promoter in advanced coating formulations.

Basic Information

Item	Detail
Product Name	Benzonitrile, 4-Isocyanato-2-(Trifluoromethyl)-
CAS No.	143782-18-7
Molecular Formula	C9H3F3N2O
Molecular Weight	212.13 g/mol
Synonyms	4-Isocyanato-2-(trifluoromethyl)benzonitrile; 2-(Trifluoromethyl)-4-isocyanatobenzonitrile; 4-Cyano-2-(trifluoromethyl)phenyl isocyanate; 2-Trifluoromethyl-4-cyanophenyl isocyanate; 4-Isocyanato-α,α,α-trifluoro-o-tolunitrile; Isocyanic acid, 4-cyano-2-(trifluoromethyl)phenyl ester; 4-CN-2-CF3-C6H3-NCO
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 4-Isocyanato-2-(Trifluoromethyl)- is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from atmospheric moisture. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Isocyanate Content (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.