Description

(R*,R*)-n-[5-[1-Hydroxy-2-[2-(4-Methoxyphenyl)-1-MethylethylAmino]Ethyl]-2-(Phenylmethoxy)Phenyl]Formamide is a high-purity, synthetically derived chiral compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical intermediate or reference standard in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting adrenergic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, process chemistry optimization, and analytical method validation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel β-adrenergic receptor ligands and related therapeutic compounds.
• Reference Standard: Used for quality control, method development, and calibration in analytical laboratories (HPLC, LC-MS) to ensure batch consistency.
• Process Chemistry Research: Employed in route scouting and optimization studies for the scalable production of complex chiral molecules.
• Biochemical Research: Acts as a tool compound for studying receptor binding affinity, selectivity, and pharmacological activity in vitro.
• Custom Synthesis: Serves as a starting material for the preparation of specialized derivatives and analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	(R*,R*)-n-[5-[1-Hydroxy-2-[2-(4-Methoxyphenyl)-1-MethylethylAmino]Ethyl]-2-(Phenylmethoxy)Phenyl]Formamide
CAS No.	143687-23-4
Molecular Formula	C33H36N2O4
Molecular Weight	524.65 g/mol
Synonyms	Formamide, N-[5-[1-hydroxy-2-[2-(4-methoxyphenyl)-1-methylethylamino]ethyl]-2-(phenylmethoxy)phenyl]-; (R*,R*)-Formamide derivative of carvedilol intermediate; 5-[(1R*)-1-Hydroxy-2-[(2R*)-2-(4-methoxyphenyl)-1-methylethylamino]ethyl]-2-(phenylmethoxy)benzamide (isomeric form); Carvedilol related compound; Benzamide, 5-[1-hydroxy-2-[2-(4-methoxyphenyl)-1-methylethylamino]ethyl]-2-(phenylmethoxy)-; Potential adrenergic receptor intermediate.
EINECS	Contact for details

Quality Control

Our (R*,R*)-n-[5-[1-Hydroxy-2-[2-(4-Methoxyphenyl)-1-MethylethylAmino]Ethyl]-2-(Phenylmethoxy)Phenyl]Formamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), chiral purity, and related substances. Our quality commitment aligns with the standards expected for pharmaceutical research materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.