Description

2-Fluoro-6-Nitrobenzonitrile is a versatile aromatic nitrile building block characterized by its strategically positioned fluorine and nitro substituents. This compound is highly valued in advanced organic synthesis for its role as a key intermediate in the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution (SNAr) to introduce functionalized aromatic rings.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Fluoro-6-Nitrobenzonitrile
CAS No.	143306-27-8
Molecular Formula	C7H3FN2O2
Molecular Weight	166.11 g/mol
Synonyms	2-Fluoro-6-nitrobenzonitrile; Benzonitrile, 2-fluoro-6-nitro-; 6-Nitro-2-fluorobenzonitrile; 2-Fluoro-6-nitro-benzonitrile; 143306-27-8; 2-Fluoro-6-nitrobenzenecarbonitrile; 2-Fluoro-6-nitro-phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.