Description

p-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its value lies in the strategic combination of an electron-withdrawing cyano group and a fluorine atom on the benzene ring, enabling precise modifications to molecular structure and properties. This compound is critically needed by R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials industries for developing active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs).
• Polymer & Material Science: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and specific dielectric properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to introduce the p-fluorobenzonitrile moiety into more complex molecules.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-value applications.

Basic Information

Product Name	p-Fluorobenzonitrile
CAS No.	143234-87-1
Molecular Formula	C7H4FN
Molecular Weight	121.11 g/mol
Synonyms	4-Fluorobenzonitrile; 4-Fluorobenzene carbonitrile; 4-Cyanofluorobenzene; p-Cyanofluorobenzene; 1-Fluoro-4-cyanobenzene; 4-Fluorophenyl cyanide; F-BENZN; FC6H4CN
EINECS	Contact for details

Quality Control

Our p-Fluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.